3-[3-(TRIFLUOROMETHYL)PHENYL]-BETA-ALANINE

3-[3-(TRIFLUOROMETHYL)PHENYL]-BETA-ALANINE - Names and Identifiers

Name	3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID
Synonyms	RARECHEM AK HW 0018 3-TrifluoroMethyl-DL-b-phenylalanine 3-[3-(TRIFLUOROMETHYL)PHENYL]-BETA-ALANINE 3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID 3-AMINO-3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID DL-3-Amino-3-(3-trifluoromethylphenyl)propanoic acid DL-3-AMINO-3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID DL-3-AMINO-3-(3-TRIFLUOROMETHYL-PHENYL)-PHENYLPROPIONIC ACID
CAS	143438-91-9
InChI	InChI=1/C10H10F3NO2/c11-10(12,13)7-3-1-2-6(4-7)8(14)5-9(15)16/h1-4,8H,5,14H2,(H,15,16)

3-[3-(TRIFLUOROMETHYL)PHENYL]-BETA-ALANINE - Physico-chemical Properties

Molecular Formula	C10H10F3NO2
Molar Mass	233.19
Density	1.361±0.06 g/cm3(Predicted)
Melting Point	210-212°C
Boling Point	295.2±40.0 °C(Predicted)
Flash Point	132.3°C
Vapor Presure	0.0007mmHg at 25°C
pKa	3.58±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.501

3-[3-(TRIFLUOROMETHYL)PHENYL]-BETA-ALANINE - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

3-[3-(TRIFLUOROMETHYL)PHENYL]-BETA-ALANINE - Introduction

3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID, also known as TFMPA, is an organic compound. The following is a description of the nature, use, formulation and safety information of TFMPA:

1. Nature:
-Appearance: TFMPA is white to yellowish crystal.
-Solubility: TFMPA is poorly soluble in water and more easily soluble in organic solvents such as ether and acetone.
-Melting point: The melting point of TFMPA is about 130-133°C.

2. Use:
- TFMPA can be used as a catalyst and ligand in organic synthesis, and is often used to catalyze the formation of C- C bonds.
- TFMPA can also be used in the field of organic Optoelectronics, such as as one of the components of optoelectronic materials.

3. Preparation method:
-The preparation method of TFMPA is more complicated. The following is a common synthesis route: first, 3-amino -3-(trifluoromethylphenyl) propionic acid methyl ester is synthesized by reaction, it is then hydrogenated to give 3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID.

4. Safety Information:
- TFMPA is irritating to the skin, eyes and respiratory tract and contact with TFMPA should be avoided.
-When using or storing TFMPA, care should be taken to prevent it from being exposed to air, light and high temperature.

Last Update：2024-04-09 02:00:42